Anticancer

Panaxydol
Catalog No: CFN92797

Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MAPK activation, cAMP, MAP kinase and ROS generation through NADPH oxidase and mitochondria. It induces the differentiation in C6 cells, may through a PI 3-K-dependent pathway.

Inulanolide A
Catalog No: CFN92801

Inulanolide A is a novel NFAT1 and MDM2 dual targeting agent and may be a clinical candidate for breast cancer therapy. Inulanolide A has potent cytotoxicity.

14-Deoxyandrographolide
Catalog No: CFN92802

14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A.

Ginsenoside Rs3
Catalog No: CFN92813

Ginsenoside Rs3 induce apoptosis, is related to the elevations of p53 and p21WAF1 in the cells.

Gamma-Tocotrienol
Catalog No: CFN92817

Gamma-Tocotrienol has antioxidant activity, it as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. Gamma-Tocotrienol is a novel blocker of the STAT3 activation pathway, it can induce the apoptosis on human gastric cancer SGC-7901 cells via mitochondria-dependent apoptosis pathway, with a potential role in future therapies for HCC and other cancers.