Anticancer

Euchrestaflavanone A
Catalog No: CFN92669

Euchrestaflavanone A is an inhibitor of MRP1-like efflux activity in human erythrocytes. It reveals potent cytotoxicities against one or more cell lines with IC 50 values in the range of 4.5–9.961μM.

Pogostone
Catalog No: CFN90555

Pogostone possesses potent anti-bacterial and anti-fungal activities, it also exhibits an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH.

Garcinone E
Catalog No: CFN92697

Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.

(-)-beta-Peltatin
Catalog No: CFN92699

(-)-beta-Peltatin has antimitotic, and antineoplastic activities.

3-Hydroxybakuchiol
Catalog No: CFN92703

3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells.