Anticancer

Enniatin B1
Catalog No: CFN97986

Enniatin B1 has antifungal effects. It induces apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Enniatin B1 also has intestinal toxicity.

Gossypol
Catalog No: CFN90561

Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.

Karounidiol
Catalog No: CFN90563

Karounidiol exhibits cytotoxicity especially against a human renal cancer, it markedly suppresses the promoting effect of TPA (1 microgram/mouse) on skin tumor formation in mice following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse).

(20S)-Protopanaxatriol
Catalog No: CFN90564

(20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows strong and selective antimicrobial activity, it also has anti-oxidant activity. (20S)-Protopanaxatriol exerts cardioprotective effects against myocardial ischemic injury, by enhancing the anti-free-radical actions of heart tissues.

Ginsenoside Rg6
Catalog No: CFN90565

Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an increase of Bax expression and decrease of Bcl-2 expression.