Quassidine B
Quassidine B is a natural product from Picrasma quassioides.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Journal of Natural Products, 2010, 73(2):167-171.
Quassidines A-D, bis-beta-carboline alkaloids from the stems of Picrasma quassioides.[Pubmed:
20095629]
METHODS AND RESULTS:
Four new bis-beta-carboline alkaloids, quassidine A,Quassidine B, quassidine C, quassidine D (1-4), together with a known alkaloid, picrasidine C (5), were isolated from the stems of Picrasma quassioides. Quassidine A (1) is the first reported bis-beta-carboline alkaloid possessing a novel cyclobutane moiety. The structures of the new compounds were determined on the basis of their 1D and 2D NMR and X-ray diffraction data.
CONCLUSIONS:
A possible biogenetic pathway for these alkaloids was proposed, and all compounds were evaluated for anti-inflammatory activity. Only quassidine A (1) showed weak activity.
