Piptocarphin A
Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Cell Prolif.2021, 54(8):e13083.
LWT2021, 150:112021.
Journal of Research in Pharmacy.2022, 26(6):p1752-1757.
Journal of functional foods2018, 171-182
Plant Archives2020, 2(1),2929-2934
The Journal of Internal Korean Medicine2015, 36(4):486-497
Korean Journal of Pharmacognosy2018, 49(4):349-361
Am J Chin Med.2023, 51(7):1675-1709.
Sci Rep.2017, 7:467-479
Sci Rep.2020, 10:4495(2020)
Related and Featured Products
J Asian Nat Prod Res. 2008 May-Jun;10(5-6):571-5.
Cytotoxic sesquiterpenoids from Vernonia bockiana.[Pubmed:
18470811 ]
METHODS AND RESULTS:
Two new sesquiterpenoids, vernobockolides A (1) and B (2), along with five known ones, piptocarphin C (3), piptocarphin F (4), Piptocarphin A (5), hirsutolide (6), and beta-d-glucopyranosyl taraxinic ester (7), were isolated from the aerial part of Vernonia bockiana. Their structures were determined by spectroscopic analysis, especially 2D NMR.
CONCLUSIONS:
Among them, compounds 2-6 showed strong cytotoxic activities against mouse lymphoid tumor cell line P388 with the IC(50) values of 1.81, 1.32, 0.77, and 0.73 microM, respectively.
