Oxohydrastinine
Oxohydrastinine shows certain antibacterial activity in vitro.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Front Pharmacol.2023, 14:1244655.
Revista Brasileira de Farmacognosia2024, 34:1091-1100.
Histol Histopathol.2022, 18518.
Viruses.2021, 13(11):2118.
Appl Biol Chem2019, 62:46
Metabolites2022, 12(6),507.
Molecules.2021, 26(9):2526.
J Ethnopharmacol.2020, 254:112733.
Chulalongkorn University2024, 4761190
Phytochem Anal.2022, doi: 10.1002
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J Med Plants Res.2011 Jan; 5.
Seven alkaloids and their antibacterial activity from Hypecoum erectum L.[Reference:
WebLink]
METHODS AND RESULTS:
From the aerial part of Hypecoum erectum L., seven alkaloids, Protopine (1), Cryptopine (2), Allocryptopine (3), Hypecorinine (4), (-)-N-Methylcanadine (5), Oxohydrastinine (6) and N-Methylcorydaldine (7) were isolated. The structures of the seven compounds were established by 1 H-NMR, 13 C-NMR, DEPT and ESI-MS analyses. Compounds 2, 5 and 7 were obtained from this plant for the first time. The antibacterial activities were investigated against six bacteria (3 gram-positive and 3 gram-negative) by disc diffusion method followed by the minimal inhibitory concentration (MIC) which was determined using a two fold serial dilution assay for the compound which have inhibitory effect.
CONCLUSIONS:
In vitro antimicrobial activities assay indicated that some compounds showed promising activities. To the best of our knowledge, this is the first report on the antimicrobial properties of these alkaloids from this plant.
Phytochemistry.1999 Jan 26;50(2):339–343.
Five alkaloids from Hypecoum leptocarpum.[Reference:
WebLink]
METHODS AND RESULTS:
Five new alkaloids, leptocarpinine, leptopine, leptopinine, leptopidine and leptopidinine were isolated, together with protopine, isohyperectine and Oxohydrastinine, from Hypecoum leptocarpum. The structures were elucidated by spectral evidence.
