(+)-Mellein

(+)-Mellein
Product Name (+)-Mellein
CAS No.: 62623-84-1
Catalog No.: CFN96915
Molecular Formula: C10H10O3
Molecular Weight: 178.18 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The leaves and stems of Stevia lucida Lagasca.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
(+)-Mellein is a natural product from Stevia lucida Lagasca.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Biochem Biophys Res Commun.2020, 522(1):40-46
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  • Oncotarget.2017, 8(64):108006-108019
  • Daru.2022, 30(2):273-288.
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  • J. Food Composition and Anal.2022, V 109:104482.
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    Isolation and characterization of (+)-mellein, the first isocoumarin reported in Stevia genus[Reference: WebLink]

    METHODS AND RESULTS:
    From the acetone extract obtained of leaves and stems of Stevia lucida Lagasca were isolated the following phenolic derivatives: (+)-Mellein [1], hispidulin [2], pectolinaringenin [3] and isosakuranetin [4]. These compounds were characterized on the basis of spectroscopic studies, including 1D- and 2D-NMR experiments.
    CONCLUSIONS:
    The literature review indicated that isocoumarins are rather rare compounds in higher plants. This gives importance to their discovery in the Stevia genus.
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