Jolkinolide E

Zhong Yao Cai. 2009 Sep;32(9):1390-2.

Studies on the chemical constituents from Euphorbia chrysocoma.[Pubmed: 20034213]

To study the chemical constituents from the aerial part of Euphorbia chrysocoma.
METHODS AND RESULTS:
All compounds were isolated and purified by many methods, including siliga gel and reversed phase RP-18 column chromatographies, preparative thin layer chromatography, Sephadex LH-20, and recrystallization. Their structures were mainly elucidated by ESI-MS and NMR spectra and their physical characters. Six compounds were isolated from the petroleum ether section from 75% ethanol extraction of the material. Their structures were identified as taraxerol (1), epitaraxerol (2), beta-sistosterol (3), beta-sitostenone (4), Jolkinolide E (5), and sesamin (6).
CONCLUSIONS:
Compounds 1, 2, 4, 5, and 6 are isolated from this plant for the first time.

Zhongguo Zhong Yao Za Zhi. 1995 Mar;20(3):169-71, 192.

Chemical constituents of Euphorbia nematocypha Hand.-Mazz.[Pubmed: 7646781]

METHODS AND RESULTS:
Four compounds were isolated from the roots of Euphorbia nematocypha. Three of them were identified as A'-neogammacer-22(29)-en-3 beta-ol (18 beta.21 alpha) (II), Jolkinolide E (III) and beta-sitoesterol (IV).
CONCLUSIONS:
Among them, II was obtained from the genus Euphorbia and III from this plant for the first time.