Esculentoside E | CAS:65649-36-7 | Manufacturer ChemFaces

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

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STUDIES ON THE ACTIVE PRINCIPLES OF THE CHINESE DRUG "SHANG LU" (PHYTOLACCA ESCULENTA VAN HO UTTE)Ⅱ. THE ISOLATION AND STRUCTURE OF ESCULENTOSIDE E AND F.[Reference: WebLink]

In a previous paper we reported the isolation of esculentoside A, B, C and D from Phytolacca eseulenta Van Houtte.In pharmacological experiments the total saponins and esculentoside A exerted considerable enhancement of phagocytic function of leucocytes and promoted DNA synthesis in mice. .
METHODS AND RESULTS:
In further search for active principles, four kinds of crystals (Ⅰ), (Ⅱ), (Ⅲ) and (Ⅳ) were isolated from the 0.01 M pH 7.3 phosphate buffer extract of the plant by silica gel column chromatography. On the basis of chemical properties and spectral data (NMR, ~(13)CNMR, UV, IR, Ms spectra), crystal (Ⅰ) was shown to be 2-hydroxyl esculentic acid, i.e. jaligonic acid which has been considered to have good antiinflammatory action; crystal (Ⅱ) was found to be 3-O-β-D-xylopyranosyl-2-hydroxylesculentic acid and was named as esculentosid E which is identical to phytolaccoside G from Phytolacca americana. Crystal (Ⅲ) is 3-O(β-D-glucopyranosyl-β-D-xylopyranosyl)_(1→4)-2-hydroxyl esculentic acid named as esculentoside F.
CONCLUSIONS:
Esculentoside E was first obtained from this plant and esculentoside F so far has not been reported in literature. Because of the scanty sample of crystal (Ⅳ), its structure is still under investigation.

Product Name	Esculentoside E
CAS No.:	65649-36-7
Catalog No.:	CFN98166
Molecular Formula:	C₃₅H₅₄O₁₁
Molecular Weight:	650.80 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The roots of Phytolacca acinosa Roxb
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
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