Cratoxylone

Cratoxylone
Product Name Cratoxylone
CAS No.: 149155-01-1
Catalog No.: CFN93577
Molecular Formula: C24H28O7
Molecular Weight: 428.5 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Yellow powder
Targets: Antifection
Source: The fruits of Garcinia mangostana
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
1. Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC₅₀ value belows 3 uM.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Int J Mol Sci.2021, 22(10):5181.
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  • Front Pharmacol.2023, 14:1244655.
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  • ACS Omega2020, 5,33,20825-20830
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    Bioassay-guided fractionation of the fruit pericarp of Pentadesma butyracea, using the antiplasmodial test, led to the isolation of a new xanthone, named pentadexanthone (1), together with six known compounds: Cratoxylone (2), α-mangostin (3), 1,3,5-trihydroxy-2-methoxyxanthone (4), garcinone E (5), (-)-epicathechin (6), and lupeol (7). The structure of 1 was elucidated by spectroscopic data analysis. An antiplasmodial assay was performed with the isolates, in which compounds 1- 3 and 5 exhibited potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC₅₀ values below 3 μM.
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