Chlorovaltrate K

Chlorovaltrate K
Product Name Chlorovaltrate K
CAS No.: 96801-92-2
Catalog No.: CFN96824
Molecular Formula: C22H33ClO8
Molecular Weight: 460.94 g/mol
Purity: >=98%
Type of Compound: Iridoids
Physical Desc.: Oil
Source: The whole plants of Valeriana jatamansi.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Chlorovaltrate K shows moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC₅₀ values of 0.89-9.76 uM.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Front Cell Dev Biol.2021, 9:764263.
  • Food Funct.2022, 13(14):7638-7649.
  • Cell Chem Biol.2019, 26(1):27-34
  • Anal Bioanal Chem.2018, 410(5):1561-1569
  • J Agric Food Chem.2015, 63(44):9869-78
  • Chem Biodivers.2023, 20(10):e202300741.
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • Journal of Medicinal Food2023, Vol.26(10).
  • J of Dentistry & Oral Health2019, 2641-1962
  • Phytomedicine.2022, 100:154058.
  • Chlorovaltrate K

    Catalog No: CFN96824
    CAS No: 96801-92-2
    Price: Inquiry(manager@chemfaces.com)
    Cerbinal

    Catalog No: CFN97119
    CAS No: 65597-42-4
    Price: Inquiry(manager@chemfaces.com)
    Cerberic acid

    Catalog No: CFN97120
    CAS No: 65597-44-6
    Price: Inquiry(manager@chemfaces.com)
    Jatairidoid A

    Catalog No: CFN95668
    CAS No: 1393577-29-1
    Price: $318/5mg
    Jatairidoid B

    Catalog No: CFN95669
    CAS No: 1393577-30-4
    Price: $318/5mg
    Jatamanvaltrate N

    Catalog No: CFN95670
    CAS No: 1395056-08-2
    Price: $318/5mg
    Valepotriate

    Catalog No: CFN90205
    CAS No: 18296-44-1
    Price: $238/20mg
    Didrovaltrate

    Catalog No: CFN96822
    CAS No: 18296-45-2
    Price: Inquiry(manager@chemfaces.com)
    IVHD-valtrate

    Catalog No: CFN96823
    CAS No: 28325-56-6
    Price: Inquiry(manager@chemfaces.com)
    Acevaltrate

    Catalog No: CFN96825
    CAS No: 25161-41-5
    Price: $138/10mg
    Phytochemistry. 2013 Jan;85:185-93.
    Characterization of chlorinated valepotriates from Valeriana jatamansi.[Pubmed: 23036722 ]

    METHODS AND RESULTS:
    HPLC-PDA-MS and TLC analysis were used to look for minor cytotoxic chlorinated valepotriates from whole plants of Valeriana jatamansi (syn. Valeriana wallichii DC.). This resulted in isolation of 15 chlorinated valepotriates, designated as chlorovaltrates A-O, together with six known analogues, (1S,3R,5R,7S,8S,9S)-3,8-epoxy-1,5-dihydroxyvalechlorine, volvaltrate B, chlorovaltrate, rupesin B, (1S,3R,5R,7S,8S,9S)-3,8-epoxy-1-O-ethyl-5-hydroxyvalechlorine, and (1R,3R,5R,7S,8S,9S)-3,8-epoxy-1-O-ethyl-5-hydroxyvalechlorine. Their structures were elucidated by spectroscopic methods including homo- and heteronuclear two-dimensional NMR experiments.
    CONCLUSIONS:
    Chlorovaltrate K, Chlorovaltrate L, Chlorovaltrate M, Chlorovaltrate N, chlorovaltrate and rupesin B showed moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC₅₀ values of 0.89-9.76 μM.
    2'-Rhamnoechinacoside

    Catalog No: CFN95035
    CAS No: 1422390-59-7
    Price: $368/10mg
    Euphorbia factor L22

    Catalog No: CFN95338
    CAS No: 1613700-09-6
    Price: $413/5mg
    Secotubeimoside I

    Catalog No: CFN95347
    CAS No: 106235-32-9
    Price: $318/10mg
    6alpha-Hydroxydehydropachymic acid

    Catalog No: CFN95412
    CAS No: 176390-67-3
    Price: $413/5mg
    Naringin 6''-acetate

    Catalog No: CFN95418
    CAS No: 139934-60-4
    Price: $318/5mg
    8-Epiloganin

    Catalog No: CFN95478
    CAS No: 79172-04-6
    Price: $318/20mg
    Quercetin 3,5-O-diglucoside

    Catalog No: CFN95486
    CAS No: 206257-35-4
    Price: $368/10mg
    12beta-Acetoxy-3,7,11,15,23-pentaoxo-lanost-8,20-dien-26-oic acid

    Catalog No: CFN95505
    CAS No: 1309931-91-6
    Price: $318/5mg
    4-O-Coumaroylquinic acid

    Catalog No: CFN95508
    CAS No: 53539-37-0
    Price: $318/5mg
    Hosenkoside D

    Catalog No: CFN95521
    CAS No: 156823-94-8
    Price: $318/5mg