Buxbodine B

Buxbodine B
Product Name Buxbodine B
CAS No.: 390362-51-3
Catalog No.: CFN98626
Molecular Formula: C26H41NO2
Molecular Weight: 399.6 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Solid
Targets: AChR
Source: The herbs of Buxus bodinieri Levl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Buxbodine B has weak anti-AChE activity with IC50 values in the range of 10.8-98μM.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Appl. Sci.2020, 10(5),1713.
  • The Catharanthus Genome2022,35-83.
  • PLoS One.2020, 15(2):e0220084.
  • Int J Mol Sci.2019, 20(21):E5488
  • J AOAC Int.2021, 104(6):1634-1651.
  • Nat Commun.2019, 10(1):2745
  • Toxins (Basel).2022, 14(12):824.
  • J. Soc. Cosmet. Sci. Korea2021, 47(1):57-63
  • Food Chem.2016, 191:81-90
  • Biomed Chromatogr.2019, 8:e4774
  • Buxbodine B

    Catalog No: CFN98626
    CAS No: 390362-51-3
    Price: Inquiry(manager@chemfaces.com)
    Buxbodine D

    Catalog No: CFN98627
    CAS No: 390362-53-5
    Price: Inquiry(manager@chemfaces.com)
    Cyclovirobuxine

    Catalog No: CFN99176
    CAS No: 860-79-7
    Price: $30/20mg
    Pachyaximine A

    Catalog No: CFN99385
    CAS No: 128255-08-3
    Price: Inquiry(manager@chemfaces.com)
    Pachysamine M

    Catalog No: CFN89007
    CAS No: 1253202-75-3
    Price: Inquiry(manager@chemfaces.com)
    Axillaridine A

    Catalog No: CFN99386
    CAS No: 128255-16-3
    Price: Inquiry(manager@chemfaces.com)
    Buxtamine

    Catalog No: CFN93072
    CAS No: 4236-73-1
    Price: Inquiry(manager@chemfaces.com)
    Steroids. 2015 Mar;95:73-9.
    Bioactive steroidal alkaloids from Buxus macowanii Oliv.[Pubmed: 25528196]

    METHODS AND RESULTS:
    Chemical investigation of the crude methanolic extract of Buxus macowanii resulted in the isolation of five new steroidal alkaloids, 31-hydroxybuxatrienone (1), macowanioxazine (2), 16α-hydroxymacowanitriene (3), macowanitriene (4), macowamine (5), along with five known steroidal bases, Nb-demethylpapillotrienine (6), moenjodaramine (7), irehine (8), Buxbodine B (9) and buxmicrophylline C (10). Structures of compounds 1-10 were elucidated with the aid of spectroscopic methods including 1D and 2D NMR techniques and mass spectrometry. Compounds 1, 3, and 4 belong to a rare class of Buxus alkaloids having Δ(1,2) 9(10→19) abeo triene system.
    CONCLUSIONS:
    All isolates were evaluated for in vitro acetylcholinesterase (AChE) inhibitory activity and found to exhibit moderate to weak anti-AChE activity with IC50 values in the range of 10.8-98μM. Compounds 1 and 6 were also moderately active in BACE1 inhibitory assay.
    Acta Botanica Yunnanica, 2001,23(3):357-62.
    Steroidal Alkaloids from Buxus bodinieri[Reference: WebLink]
    Five new steroidal alkaloids have been isolated from Buxus bodinieri Lévl.,a common ornamental in South-China.
    METHODS AND RESULTS:
    On the basis of IR, UV, MS, NMR spectral analyses and chemical evidence, the chemical structure of these new steroidal alkaloids were deduced as: buxbodine A (1)(20α- dimethylamino-9β,19-cyclo-4,4,14α-trimethy-5α-pregnane); Buxbodine B (2)(16β-hydroxy-20α-dimethylamino-9β,19-cyclo-4,4,14α-trimethy-5α-pregn-1(2)-en-3-one); buxbodine C (3)(3β-dimethylamino-9β,19-cyclo-4,4,14α-trimethy-5α-pregn-6(7), 17 (20)-dien-16-one), buxbodine D (4)(3β-dimethylamino-20α-acetoxylamino-9β,19-cyclo -4,4,14α-trimethy-5α-pregn-6(7)-ene) and buxbodine E (5)(3(-dimethylamino-20α-amino -9β,19-cyclo-4,4,14α-trimethy-5α-pregn-6(7)-ene), respectively.
    1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside

    Catalog No: CFN95095
    CAS No: 87686-87-1
    Price: $218/10mg
    Leachianol F

    Catalog No: CFN95147
    CAS No: 164123-50-6
    Price: $318/5mg
    24-Hydroxymomordicine III

    Catalog No: CFN95169
    CAS No: N/A
    Price: $318/5mg
    19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene

    Catalog No: CFN95217
    CAS No: 1011714-20-7
    Price: $318/5mg
    Phyllanthusiin C

    Catalog No: CFN95260
    CAS No: 142674-52-0
    Price: $318/5mg
    Batatasin V

    Catalog No: CFN95320
    CAS No: 65817-45-0
    Price: $318/5mg
    Oxytroflavoside B

    Catalog No: CFN95490
    CAS No: 1391144-81-2
    Price: $318/10mg
    trans-Cinnamoyl beta-D-glucoside

    Catalog No: CFN95497
    CAS No: 13080-39-2
    Price: Inquiry(manager@chemfaces.com)
    12beta-Acetoxy-3,7,11,15,23-pentaoxo-lanost-8,20-dien-26-oic acid

    Catalog No: CFN95505
    CAS No: 1309931-91-6
    Price: $318/5mg
    5-O-Coumaroylquinic acid

    Catalog No: CFN95507
    CAS No: 32451-86-8
    Price: $318/5mg