7-Epi-10-deacetylcephalomannine
7-Epi-10-deacetylcephalomannine is a natural product from Taxus sumatrana.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
bioRxiv - Biochemistry2023, 541790.
JPC-Journal of Planar Chromatography2023, 36:179-190
ACS Pharmacol. Transl. Sci.2023, 3c00129.
Kyung Hee University2024, rs-3888374
BMC Microbiol.2019, 19(1):78
J Immunol.2023, ji2200727.
Sci Rep.2024, 14(1):23786.
Food Sci Biotechnol.2021, 30(2):217-226.
Cells.2023, 12(1):168.
Food Res Int.2024, 197(Pt 1):115244.
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Chem Pharm Bull (Tokyo). 1995 Feb;43(2):365-7.
Taxol and its related taxoids from the needles of Taxus sumatrana.[Pubmed:
7728941]
METHODS AND RESULTS:
Through bioassay-guided separation of the chemical constituents of the needles of Taxus sumatrana, taxol (1), cephalomannine (2), and a new taxoid 19-hydroxy-13-oxobaccatin III (8) have been isolated together with 7-epi-10-deacetyltaxol (3), 7-Epi-10-deacetylcephalomannine (4), baccatin III (5), 19-hydroxybaccatin III (6), and 10-deacetyl-13-oxobaccatin III (7).
CONCLUSIONS:
The chemical structure of 8 has been elucidated on the bases of its chemical and physicochemical properties.
