6-Hydroxybenzofuran-2(3H)-one
Molecular docking studies of all compounds( thirteen novel 6-Hydroxybenzofuran-2(3H)-one(6-hydroxybenzofuran-3(2H)-one)) on the active sites of microbial enzymes indicated a possible target N-myristoyltransferase (NMT).
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Korean Journal of Plant Resources2021, 34(1):52-58.
J. Pharm. Res. Int.2022, 34(58): pp.1-14.
Enzyme and Microbial Technology2022, 110002.
Heliyon2020, 6(6):e04337.
Journal of Food and Drug Analysis2023, 31(3), 9.
Int J Med Sci.2024, 21(15):2883-2896
Phytomedicine.2019, 65:153089
Neuroscience.2024, 559:77-90.
Genes (Basel).2021, 12(7):1024.
Sci Rep. 2017, 17332(7)
Related and Featured Products
Letters in Drug Design & Discovery, 2013,10(9):798-807.
Synthesis, Antimicrobial Activities and Molecular Docking Studies of Novel 6-Hydroxybenzofuran-3(2H)-one Based 2,4-Disubstituted 1,3-Thiazoles.[Reference:
WebLink]
METHODS AND RESULTS:
Synthesis, characterization and investigation of antibacterial and antifungal activities of thirteen novel 6-Hydroxybenzofuran-2(3H)-one(6-hydroxybenzofuran-3(2H)-one)
based 2,4-disubstituted 1,3-thiazoles are presented. Their structures were determined using NMR, FAB MS and HRMS analyses. The results of microbiological screening reveal that three derivatives containing fluorine, bromine and hydrogen substituents at the phenyl ring are the most active antimicrobial compounds.
CONCLUSIONS:
Molecular docking studies of all compounds on the active sites of microbial enzymes indicated a possible target N-myristoyltransferase (NMT).
