3-O-beta-D-Glucopyranosylplatycodigenin

3-O-beta-D-Glucopyranosylplatycodigenin
Product Name 3-O-beta-D-Glucopyranosylplatycodigenin
CAS No.: 38337-25-6
Catalog No.: CFN90950
Molecular Formula: C36H58O12
Molecular Weight: 682.85 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Platycodon grandiflorum.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $268/5mg
3-O-beta-D-Glucopyranosylplatycodigenin may have in vitro anti-proliferative activity against the HSC-T6 cell line.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Molecules. 2012 Dec 13;17(12):14899-907.
    Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells.[Pubmed: 23519261 ]

    METHODS AND RESULTS:
    Two new oleanane-type triterpenoids, named platycodonoids A and B (1, 2), together with five known saponins, including platycodin D (3), deapioplatycodin D (4), 3-O-β-D-glucopyranosyl polygalacic acid (5), 3-O-beta-D-Glucopyranosylplatycodigenin (6) and polygalacin D (7), were isolated from the roots of Platycodon grandiflorum. On the basis of spectral data and chemical evidence, the structures of the new compounds were elucidated as 2β,3β,23,24-tetrahydroxy-28-nor-olean-12-en-16-one (1) and 2β,3β,23,24- tetrahydroxy-28-nor-olean-12-en-16-one-3-O-β-D-glucopyranoside (2).
    CONCLUSIONS:
    Compounds 1-7 were evaluated for their in vitro anti-proliferative activity against the HSC-T6 cell line.
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    METHODS AND RESULTS:
    Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data. Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-Glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-Glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).
    CONCLUSIONS:
    Compounds 1,3 and 5 were isolated from this plant for the first time.
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