3-Hydroxy-3-acetonyloxindole
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Acta Physiol Pharmacol Latinoam. 1986;36(4):391-5.
Biological studies on indole derivatives. I. Synthesis and pharmacological studies of 2-oxo-3-indolyl derivatives.[Pubmed:
3604703]
METHODS AND RESULTS:
Two compounds, 3-Hydroxy-3-acetonyloxindole (I) and compound 3-acetonylidene-oxindole (II) were synthesized by a convenient method, and their pharmacological/toxicological effects were studied in rabbit.
CONCLUSIONS:
These compounds produced transitory effects on serum enzymes. The cholesterol mobilizing effect is more prominent with compound (I).
J Pharm Sci. 1980 Oct;69(10):1235-7.
Synthesis of potential anticonvulsants: condensation of isatins with acetone and related ketones.[Pubmed:
6158569]
METHODS AND RESULTS:
Substituted isatins were condensed with acetone and other ketones to give analogs of 3-Hydroxy-3-acetonyloxindole. Some of these alcohols were dehydrated. Several compounds with anticonvulsant activity were obtained.
