11beta-Hydroxycedrelone
11β-Hydroxycedrelone has cytotoxic activity, it exhibits moderate inhibitory activity against HL-60 cell line with the IC50 values of 8.9 uM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Pharmaceuticals (Basel).2022, 15(8):982.
Food Science and Biotechnology2015, 2205-2212
Food Sci Nutr.2019, 8(1):246-256
Biomed Pharmacother.2023, 166:115329.
J Korean Med Ophthalmol Otolaryngol Dermatol2023, 36(1):21-39.
Hum Exp Toxicol.2023, 42:9603271231171642.
Food Chem Toxicol.2024, 186:114589.
BMC Complement Altern Med.2017, 17(1):393
Korean J. Medicinal Crop Sci.2018, 26(2):148-156
Curr Issues Mol Biol.2023, 45(3):2136-2156.
Related and Featured Products
Asian Journal of Chemistry, 2015, 27(6):2109-2111.
Isolation of 11b-Hydroxycedrelone from Walsura yunnanensis and its Cytotoxic Activity.[Reference:
WebLink]
METHODS AND RESULTS:
11beta-Hydroxycedrelone was isolated from the twigs and leaves of Walsura yunnanensis C. Y. Wu. Its structure was established on the basis of spectroscopic methods. 11beta-Hydroxycedrelone featured a typical rearranged A-ring structure of this compound class.
CONCLUSIONS:
Cytotoxic evaluation showed that its exhibited moderate inhibitory activity against HL-60 cell line with the IC50 values of 8.9 μM.
J Nat Prod. 2000 Jul;63(7):947-51.
Tetranortriterpenoids from Walsura yunnanensis.[Pubmed:
10924171]
METHODS AND RESULTS:
Five new tetranortriterpenoids-walsurin (1), isowalsuranolide (2), walsuranolide (3), 11beta-acetoxywalsuranolide (4), and 20, 22-dihydro-22,23-epoxywalsuranolide (5)-and three new natural tetranortriterpenoids-11beta-hydroxydihydrocedrelone (6), 11beta-acetoxydihydrocedrelone (7), and 11beta-Hydroxycedrelone (8)-together with a known tetranortriterpenoid, cedrelone (9), were isolated from the bark of Walsura yunnanensis. The structures of 1-8 were determined on the basis of spectral evidence.
