1-Hydroxytropacocaine
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Toxicol Appl Pharmacol.2021, 427:115668.
Nutrients.2023, 15(4):950.
Chemical Engineering Journal2024, 500:157110
Sci Rep. 2017, 17332(7)
BMC Complement Med Ther. 2020, 20(1):94.
Toxicol Appl Pharmacol.2022, 434:115815.
Phytochemistry Letters2021, 43:80-87.
Mol Biol Rep.2023, 50(5):4029-4038.
Sci Rep.2017, 7:467-479
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Phytochemistry,1994,36(2):357-360.
1-Hydroxytropacocaine: An abundant alkaloid of Erythroxylum novogranatense var. Novogranatense and var. Truxillense[Reference:
WebLink]
A new alkaloid, 1-Hydroxytropacocaine, was isolated from leaves of greenhouse-cultivated Erythroxylum novogranatense var. novogranatense and identified.
METHODS AND RESULTS:
Quantitative levels of this alkaloid in dry leaf were similar to those for cocaine, i.e. 0.3–0.5% w/w. 1-Hydroxytropacocaine was also detected at 0.04–0.07% w/w (relative to dry coca leaf) in greenhouse-cultivated Erythroxylum novogranatense var. truxillense and at similar levels in Erythroxylum novogranatense var. novogranatense, grown at a tropical site other than in South America.
CONCLUSIONS:
The presence of 1-Hydroxytropacocaine was <0.01% w/w (relative to dry coca leaf) in suspected Erythroxylum novogranatense var. novogranatense and Erythroxylum coca var. coca, field-cultivated in Colombia and Bolivia, respectively.
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