Neuroprotection

Nicotiflorin
Catalog No: CFN99830

Nicotiflorin shows potent antiglycation activity and neuroprotection effects, it has protective effects on cerebral ischemic damage, reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats.
trans-Hinokiresinol
Catalog No: CFN99834

Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) are estrogen agonists, they possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen- dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist. They have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation.
Sesamolin
Catalog No: CFN99799

Sesaminol possesses antioxidative activity, can inhibit lipid peroxidation in rat liver and kidney. It also shows neuroprotection effect on hypoxic neuronal and PC12 cells through the suppression of ROS generation and MAPK activation.
Honokiol
Catalog No: CFN99902

Honokiol has antibacterial, anti-angiogenesis, antidepressant-like, antioxidant, anti-inflammatory and anti-cancer effects. It inhibited the activation of Akt and enhances the phosphorylation of ERK1/ERK2. It can improve learning, memory impairments and neuroinflammatory processes induced by SCOP in mice, by inhibition of AChE activity.
Myricitrin
Catalog No: CFN99840

Myricitrin exhibits hepatoprotective, anti-inflammatory,antioxidant, anti-allergic, antinociception, anxiolytic-like, and antipsychotic-like effects. Myricitrin can be used as a drug candidate for the treatment of cardiovascular diseases, by effectively protecting cells from ox-LDL-induced endothelial cell apoptosis and reducing atherosclerotic plaque formation. Myricitrin is also a nitric oxide (NO) and protein kinase C (PKC) inhibitor that has central nervous system activity.