Neuroprotection

Glabridin
Catalog No: CFN99731

Glabridin is a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory, which has antioxidative,anti-inflammatory, antimalarial, estrogen receptor agonism, anti-metastasis, anti-melanogenesis and neuroprotective effects. Glabridin may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells.

Biochanin A
Catalog No: CFN99734

Biochanin A, an O-methylated natural isoflavonoid classified as phytoestrogen, is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively. Biochanin A has hypoglycemic, antilipemic,anti-tumorigenesis, anti-oxidation, and anti-inflammatory properties, it also has neuroprotective effects in cerebral ischemia/reperfusion by inhibiting inflammatory response and the inactivation of p38 signaling pathway. Biochanin A could inhibit Methicillin-resistant Staphylococcus aureus efflux system through reducing pathogen' s expression of nor A and norA protein.

Ethyl ferulate
Catalog No: CFN99767

Ethyl ferulate has anti-inflammatory property, can reduce HIV replication, it shows inhibitive effect on platelet congregation induced by ADP. It also is a potent inducer of HO-1 for the protection of brain cells against oxidative and neurodegenerative conditions.

Theophylline
Catalog No: CFN99768

Theophylline is a competitive nonselective phosphodiesterase inhibitor and nonselective adenosine receptor antagonist, which is the most widely used anti-asthma drug worldwide and is classified as a bronchodilator. It has antiinflammatory, and immunomodulatory actions, it also can antagonize flurazepam-induced depression of cerebral cortical neurons.

D-(+)-Glucose
Catalog No: CFN99769

Dextrose, a simple sugar (monosaccharide), is an important carbohydrate in biology, it exhibits marked antibacterial activity against Staphylococcus aureus,Escherichia coli and Pyocyanine. D-(+)-Glucose can prevent MPP+ toxicity, attenuate the loss of ATP, but do not reverse the complete inhibition of mitochondrial O2 consumption (MOC).