Inhibitors

Gnetumontanin B
Catalog No: CFN92853

Gnetumontanin B shows potent inhibition of TNF-alpha.

Viniferin
Catalog No: CFN92854

α-Viniferin has anti-oxidant and anticancer activities, it strongly inhibits the activities of the two CYPs dose dependently. α-Viniferin suppresses the expression of proinflammatory genes iNOS and COX-2 in the early stage of inflammation by inhibiting the Akt/PI3K-dependent NF-κB activation and inhibits the production of proinflammatory mediators NO and PGE2 in the late stage by stimulating Nrf2-mediated HO-1 signaling pathway in LPS-stimulated BV2 microglial cells. ɛ-Viniferin and vincristine can enhance the anti-tumor effects efficiently by inducing HepG2 cell apoptosis.

4',7-Dihydroxyflavone
Catalog No: CFN92855

4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.

Tracheloside
Catalog No: CFN90597

Tracheloside significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).

Lasiodiplodin
Catalog No: CFN97898

Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. Lasiodiplodin inhibits electron transport chain.