Antiviral

Triptonine B
Catalog No: CFN92116

Triptonine B demonstrates potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000.

Sikokianin A
Catalog No: CFN92155

Sikokianin A shows in vitro antiviral activity against HBsAg secretion.

Sugiol
Catalog No: CFN92187

Sugiol has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the inflammatory cytokines of IL-1beta and TNF-alpha could be attributed to a reduction of the ROS that leads to a decrease in the phosphorylation of MAPKs.

Schisanlactone A
Catalog No: CFN92212

Schisanlactone A is a dimerization inhibitor, with an IC50 value of 5.0 microg/mL; it also shows appreciable inhibitory activity against HIV-1 protease with the IC50 value of 20 microM. Schisanlactone A shows cytotoxicity against KB (a human epidermal carcinoma) cells with the IC50 value of 63.3 uM.

Norwogonin
Catalog No: CFN92218

Norwogonin(IC 50 = 1.1 microM) shows potent inhibitory activity toward VHR.