Anticholinesterase

Cyclomorusin
Catalog No: CFN97714

Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophils. Cyclomorusin , neocyclomorusin and kuwanon C inhibited cholinesterase enzyme in a dose-dependent manner with K(i) values ranging between 3.1 and 37.5 uM and between 1.7 and 19.1 uM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively.

1,2-Didehydrotanshinone IIA
Catalog No: CFN92165

1,2-Didehydrotanshinone IIA shows inhibitory effects against acetyl- (AChE) and butyrylcholinesterase (BChE). It also possesses metal-chelation capacity.

Mahanimbine
Catalog No: CFN92197

Mahanimbine inhibits AChE activity in a dose-dependent manner. Mahanimbine can lower the absorption of dietary fat resulting in dietary fat excretion, it can prevent high-fat diet (HFD)-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with the restricted progression of systemic inflammation and oxidative stress. Mahanimbine and mangiferin increases the glucose utilization in a dose-dependent manner, can prevent obesity and use in management of diabetes.

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone
Catalog No: CFN92321

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone inhibits cholinesterase enzyme in a dose-dependent manner against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes.It shows better tyrosinase inhibitory activities than kojic acid.

1,3,5-Trihydroxyxanthone
Catalog No: CFN92399

1,3,5-Trihydroxyxanthone has selective inhibitory activity on platelet aggregation induced by adenosine diphosphate.