Anticancer

Ursolic acid
Catalog No: CFN97259

Ursolic acid is a potential PPARγagonist, which has anti-tumor, chemopreventive, hepatoprotective, anti-inflammatory, antioxidant, antidepressant-like, antimicrobial activities, and anti-asthmatic effects. Ursolic acid also has antihyperlipidemic, hypoglycemic and direct cardiac effect, its antihypertensive effect is attributed to its potent diuretic-natriuretic-saluretic activity. Ursolic acid regulates NF-κB, VEGF, COX-2, Nrf2, ARE, IL-5, IL-13, IL-17and MAPK signaling pathways.

Crosemperine
Catalog No: CFN00362

Crosemperine has antitumor and antimicrobial activity.

19-Hydroxybaccatin III
Catalog No: CFN97267

19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol are new antitumor taxanes from Taxus wallichiana.

Madurensine
Catalog No: CFN00380

Madurensine and doronenine show moderate cytotoxicity on cancerous U-937 cells (IC(50) values: 47.97 and 29.57 M respectively). Madurensine induces autophagy, which in prolonged circumstances may lead to autophagic cell death.

Spectabiline
Catalog No: CFN00386

Spectabiline shows tumor-inhibitory properties against one or more test tumors. Spectabiline, monocrotaline, sarracine, lasiocarpine, 7-angelylheliotridine, heliotrine and senecionine have similar antagonistic potencies against responses to both acetylcholine and histamine.