Antagonists

Delaminomycin A
Catalog No: CFN00113

Delaminomycin A is an immunomodulator, it is a cell adhesion inhibitor and extracellular matrix receptor antagonist. Delaminomycin A is active against gram-positive bacteria.

Janolusimide
Catalog No: CFN00120

Janolusimide is a neurotoxin and atropine antagonist.

Stigmasterol
Catalog No: CFN97326

Stigmasterol is used as a precursor in the manufacture of synthetic progesterone, it is an antagonist of the bile acid nuclear receptor FXR, which has anti-inflammatory, thyroid inhibitory, cholesterol-lowering, antiperoxidative and hypoglycemic effects; it has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers. Stigmasterol inhibits the NF-kappaB pathway.

Lobelin
Catalog No: CFN00445

Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing.

Yohimbine
Catalog No: CFN90147

Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. Yohimbine may augment extinction learning without significant side effects, and as a therapeutic augmentation strategy for exposure therapy in social anxiety disorder. Yohimbine can be used as antagonistic agents against medetomidine-induced diuresis in healthy cats; it inhibits ATP-sensitive K+ channels in mouse pancreatic beta-cells.