RA-XI
RA-XI shows potent antitumor activity against P-388.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Applied Biological Chem. 2020, 26(63).
J Korean Society of Food Science & Nutrition2021, 50(9): 962-970
Food Funct.2022, 13(13):6923-6933.
Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
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Phytochemistry Letters2015, 243-247
FEMS Microbiol Lett.2017, 364(11)
Molecules.2022, 27(19):6681.
Planta Medica International2022, 9(01):e108-e115.
Molecules.2023, 28(5):2376.
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Chem Pharm Bull (Tokyo). 1992 May;40(5):1352-4.
New antitumor bicyclic hexapeptides, RA-XI, -XII, -XIII and -XIV from Rubia cordifolia.[Pubmed:
1394660]
METHODS AND RESULTS:
Four new bicyclic hexapeptides, named as RA-XI, -XII, XIII and -XIV were isolated from Rubia cordifolia and showed potent antitumor activities against P-388. The structures were elucidated from spectroscopic and chemical evidences.
CONCLUSIONS:
RA-XII, XIII and -XIV were proved to be unique bicyclic hexapeptidic glucosides.
