Isorhamnetin-3-O-neohespeidoside

Isorhamnetin-3-O-neohespeidoside
Product Name Isorhamnetin-3-O-neohespeidoside
CAS No.: 55033-90-4
Catalog No.: CFN99744
Molecular Formula: C28H32O16
Molecular Weight: 624.54 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The barks of Rhamnus purshiana
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $60/20mg
Isorhamnetin 3-O-neohesperoside is the major active substance of Puhuang, a traditional herb medicine widely used in clinical practice to tackle many chronic diseases. It has significant biological and pharmacological activities, including antioxidant, antiatherogenic and antimicrobial effects.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Molecules.2016, 21(6)
  • Tissue Cell.2022, 78:101901.
  • Nutrients.2023, 15(6):1335.
  • Antioxidants (Basel).2023, 12(12):2078.
  • Cells.2021, 10(10):2633.
  • Int J Mol Sci.2020, 21(19),7070.
  • Hum Exp Toxicol.2023, 42:9603271221145386.
  • BMC Complement Altern Med.2018, 18(1):221
  • Molecules.2021, 26(19):6032.
  • Front Pharmacol.2018, 9:756
  • Rhamnetin 3-galactoside

    Catalog No: CFN95116
    CAS No: 62858-07-5
    Price: $318/10mg
    Rhamnetin 3-glucoside

    Catalog No: CFN95839
    CAS No: 27875-34-9
    Price: $318/5mg
    Rhamnetin 3-O-gentiobioside

    Catalog No: CFN95835
    CAS No: 1786990-15-8
    Price: $318/5mg
    Rhamnetin 3-sophoroside

    Catalog No: CFN95837
    CAS No: 259234-17-8
    Price: $318/5mg
    Isorhamnetin 3-glucuronide

    Catalog No: CFN90568
    CAS No: 36687-76-0
    Price: Inquiry(manager@chemfaces.com)
    Isorhamnetin 3-sambubioside

    Catalog No: CFN95874
    CAS No: 142059-76-5
    Price: $318/5mg
    Isorhamnetin-3-O-neohespeidoside

    Catalog No: CFN99744
    CAS No: 55033-90-4
    Price: $60/20mg
    Narcissoside

    Catalog No: CFN99773
    CAS No: 604-80-8
    Price: $70/20mg
    Isorhamnetin-3-O-glucosyl-(1->4)-O-rhamnoside

    Catalog No: CFN95723
    CAS No: 1135753-17-1
    Price: $318/5mg
    Astragaloside

    Catalog No: CFN99170
    CAS No: 17429-69-5
    Price: Inquiry(manager@chemfaces.com)
    J Sep Sci . 2019 Jul;42(14):2426-2434.
    A rapid and efficient extraction method based on industrial MCM-41-miniaturized matrix solid-phase dispersion extraction with response surface methodology for simultaneous quantification of six flavonoids in Pollen typhae by ultra-high-performance liquid chromatography[Pubmed: 31077572]
    Abstract An industrial MCM-41-miniaturized matrix solid-phase dispersion extraction coupled with response surface methodology was explored to determine L-epicatechin, typhaneoside, Isorhamnetin-3-O-neohespeidoside, naringenin, kaempferol, and isorhamnetin in Pollen typhae by ultra-high performance liquid chromatography connected to a photodiode array detection. Several variables were optimized in detail, including mesh number of sieve, type of adsorbent, mass ratio of sample to adsorbent, grinding time, methanol concentration, and elution volume. Central composite design was applied to optimize the best conditions for the maximum yields of the total flavonoids. The results displayed a good linear relationship (R > 0.9992) and the recoveries ranged from 92.9 to 103% (RSD < 4.53%) of the six flavonoids. The optimal method with high efficiency and low consumption was obviously better than heating reflux and ultrasonic extraction. It was proven that the developed industrial MCM-41-miniaturized matrix solid-phase dispersion extraction coupled with simple ultra-high performance liquid chromatography method could be a rapid and efficient tool for extraction and determination of flavonoids in natural products. Keywords: MCM-41; miniaturized matrix solid-phase dispersion extraction; response surface methodology; traditional Chinese medicine; ultra-high-performance liquid chromatography.
    J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jan 1;974:131-7.
    Measurement of hydroxysafflor yellow A in human urine by liquid chromatography-tandem mass spectrometry.[Pubmed: 25463208]

    METHODS AND RESULTS:
    A rapid and specific high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for the quantification of hydroxysafflor yellow A (HSYA) in human urine with Isorhamnetin-3-O-neohespeidoside as internal standard (IS). HSYA and IS were extracted from urine samples by simple solid-phase extraction and separated on an Agilent Zorbax SB C18 column (4.6 mm × 150 mm, 5 μm) with the mobile phase of 0.2 mM ammonium acetate: methanol (30/70, v/v) at a flow rate of 0.4 mL/min. Polar endogenous interferences eluted in 0.1-2.5 min were switched into waste channel by the Valve Valco, to reduce the possible matrix effect for MS detection in each run. The MS detection of analytes was performed on a tandem mass spectrometer equipped with an electrospray ionization source in negative mode using multiple-reaction monitoring. The MS/MS ion transitions monitored were m/z 611.3→491.2 for HSYA and m/z 623.2→299.2 for IS. The method was fully validated for selectivity, sensitivity, linearity, precision, accuracy, recovery, matrix effect and stability, and then was applied to the urinary excretion study of injectable powder of pure HSYA in healthy Chinese volunteers for the first time.
    CONCLUSIONS:
    The results suggested that urine was the main excretion way of HSYA in healthy volunteers, further demonstrating the feasibility and necessity of our current method.
    New Compound 1

    Catalog No: CFN95152
    CAS No: N/A
    Price: $318/5mg
    Astin A

    Catalog No: CFN95187
    CAS No: 151201-75-1
    Price: $318/10mg
    Prionanthoside

    Catalog No: CFN95206
    CAS No: 161842-81-5
    Price: $318/10mg
    Arganine B

    Catalog No: CFN95281
    CAS No: 144425-21-8
    Price: $318/5mg
    Grosvenorin 2''-glucoside

    Catalog No: CFN95282
    CAS No: N/A
    Price: $318/5mg
    Japondipsaponin E1

    Catalog No: CFN95354
    CAS No: 175586-66-0
    Price: $318/5mg
    Mucronulatol

    Catalog No: CFN95386
    CAS No: 20878-98-2
    Price: $318/5mg
    3',4',5',5,7-Pentamethoxyflavanone

    Catalog No: CFN95414
    CAS No: 479672-30-5
    Price: $218/20mg
    4-O-Caffeoyl-3-O-syringoylquinic acid

    Catalog No: CFN95430
    CAS No: 1207645-17-7
    Price: $413/5mg
    Ganoderic acid Df

    Catalog No: CFN95514
    CAS No: 1352033-73-8
    Price: $318/5mg