Isocarapanaubine
Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Chem Pharm Bull (Tokyo). 2010 Aug;58(8):1085-7.
Oppositinines A and B: new vasorelaxant beta-carboline alkaloids from Neisosperma oppositifolia.[Pubmed:
20686264]
METHODS AND RESULTS:
A phytochemical study on the bark of Neisosperma oppositifolia (Apocynaceae) yielded two new beta-carboline indole alkaloids, oppositinines A (1) and B (2), together with five known alkaloids, isoreserpiline, Isocarapanaubine, vobasine, 10-methoxydihydrocorynantheol-N-oxide, and ochropposinine oxindole. Structural elucidation of 1 and 2 was performed using 2D NMR methods.
CONCLUSIONS:
Oppositinines A (1) and B (2) showed potent vasorelaxant effects on the rat aorta.
Natural Medicines,1999, 53(5):272.
Cytotoxic Alkaloids from the Barks of Ochrosia elliptica(Natural Medicine Note)[Reference:
WebLink]
METHODS AND RESULTS:
Reserpiline (3) and Isocarapanaubine (4), along with ellipticine (1) and 9-methoxyellipticine (2), were isolated as the cytotoxic constituents from the barks of Ochrosia elliptica.
