Coccinic acid

Coccinic acid
Product Name Coccinic acid
CAS No.: 107783-45-9
Catalog No.: CFN99083
Molecular Formula: C30H46O3
Molecular Weight: 454.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Targets: Estrogen receptor | Progestogen receptor
Source: The roots of Kadsura coccinea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Coccinic acid shows inhibitory effects against colorectal carcinoma HCT-15 and oral epithelial cell line KB-3-1.Mixture of coccinic acid and anwuweizonic acid shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro, suggests that it has antifertility activity.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Oxid Med Cell Longev.2022, 2022:5888636.
  • JMSACL2023, 09.002
  • Molecules.2023, 28(2):727.
  • Nutrients.2020, 12(11):3448.
  • Food Bioscience2023, 52:102412
  • Plant Biotechnol (Tokyo).2024, 41(3):267-276.
  • Clin Exp Pharmacol Physiol.2020, doi: 10.1111
  • Oxid Med Cell Longev.2020, 2020:8887251.
  • Natural Product Communications2022, 7(3):1-7.
  • Int J Mol Sci.2021, 22(11):5503.
  • Ganoderic acid beta

    Catalog No: CFN95537
    CAS No: 217476-76-1
    Price: $413/5mg
    Ganoderic acid GS-1

    Catalog No: CFN95571
    CAS No: 1206781-64-7
    Price: $413/5mg
    Ganoderic acid GS-2

    Catalog No: CFN95549
    CAS No: 1206781-65-8
    Price: $413/5mg
    New compound 21

    Catalog No: CFN95560
    CAS No: N/A
    Price: $413/5mg
    Ganoderic acid Y

    Catalog No: CFN90294
    CAS No: 86377-52-8
    Price: Inquiry(manager@chemfaces.com)
    Ganoderic acid SZ

    Catalog No: CFN97426
    CAS No: 865543-37-9
    Price: Inquiry(manager@chemfaces.com)
    Ganoderic acid S

    Catalog No: CFN99066
    CAS No: 104759-35-5
    Price: $568/5mg
    Ganoderic acid TN

    Catalog No: CFN90298
    CAS No: 112430-64-5
    Price: $318/5mg
    Ganoderic acid X

    Catalog No: CFN92996
    CAS No: 86377-53-9
    Price: $463/5mg
    Ganoderic acid Jb

    Catalog No: CFN92997
    CAS No: 112430-68-9
    Price: Inquiry(manager@chemfaces.com)
    Pharm Biol. 2013 Sep;51(9):1204-7.
    Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens.[Pubmed: 23883077]

    METHODS AND RESULTS:
    Nine known compounds were obtained, including four lignans, epischisandrone (1), tigloylgomisin P (2), cagayanone (3) and (-)-gomisin L₂ (4), together with five triterpenoids, micranoic acid B (5), lancifodilactone H (6), Coccinic acid (7), schisanlactone B (8) and anwuweizonic acid (9).
    CONCLUSIONS:
    Compounds 2-6 and 8 showed moderate to marginal cytotoxicity, with GI₅₀ values of 11.83-35.65 μM.
    Chinese Journal of Modern Applied Pharmacy, 2002, 19(2):103-5.
    Antifertility Triterpenoid Acids from Kadsura angustifolia.[Reference: WebLink]
    To isolate and characterize bioactive compounds from the stems of Kadsura angustifolia .
    METHODS AND RESULTS:
    The compounds were extracted with solvent,isolated by column chromatography and identified by the spectroscopic methods. eight compounds and a mixture of two triterpenoid acids were isolated and identified as epi anwuweizic acid (1),shikimic acid (2),(+) catechin (3),poriferast 5 en 3β,7α diol (4),β sitosterol (5),daucosterol (6),cerotic acid 1 monoglyceride (7) and behenic acid 1 monoglyceride (8),and mixiture of Coccinic acid (9) and anwuweizonic acid (10).
    CONCLUSIONS:
    Mixture of 9 and 10 showed significant inhibitory activity against human decidual cells and rat luteal cells in vitro . Compounds 2~4,7 and 8 were first reported in the family Schisandraceae,and compounds 1,5,6,9 and 10 were isolated from K.angustifolia for the first time.
    Planta Med. 1986 Dec;(6):492-3.
    Triterpenoids from Roots and Stems of Kadsura coccinea.[Pubmed: 17345419]

    METHODS AND RESULTS:
    24-Methylenecycloartenone ( 1), kadsuric acid ( 2) and a new triterpenoid acid named Coccinic acid ( 3A) were isolated from the ether soluble fraction of the dried roots and stems of Kadsura coccinea.
    Alloisoimperatorin

    Catalog No: CFN95012
    CAS No: 35214-83-6
    Price: $338/5mg
    Iristectorin A

    Catalog No: CFN95037
    CAS No: 37744-61-9
    Price: $318/20mg
    Isololiolide

    Catalog No: CFN95106
    CAS No: 38274-00-9
    Price: $318/5mg
    Methylgomisin O

    Catalog No: CFN95236
    CAS No: 1276654-07-9
    Price: $318/5mg
    Notoginsenoside L13

    Catalog No: CFN95332
    CAS No: 2485859-56-9
    Price: $318/5mg
    Tortoside B (Manglieside E)

    Catalog No: CFN95390
    CAS No: 190655-17-5
    Price: $413/5mg
    Oblonganoside D

    Catalog No: CFN95460
    CAS No: 943021-91-8
    Price: $318/5mg
    2,6-Dihydroxyacetophenone-4-O-[4',6'-(S)-hexahydroxydiphenoyl]-beta-D-glucose

    Catalog No: CFN95470
    CAS No: 1781226-44-5
    Price: $318/5mg
    Hosenkoside D

    Catalog No: CFN95521
    CAS No: 156823-94-8
    Price: $318/5mg
    Gossypetin 3-sophoroside-8-glucoside

    Catalog No: CFN95528
    CAS No: 77306-93-5
    Price: $318/5mg