1-Methoxyberberine
1-Methoxyberberine chloride is a potential antifungal agent.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Folia Microbiol (Praha). 2003;48(5):605-9.
Two plant alkaloids isolated from Corydalis longipes as potential antifungal agents.[Pubmed:
14976716]
METHODS AND RESULTS:
The alkaloids N-methylhydrasteine hydroxylactam and 1-Methoxyberberine chloride were isolated from Corydalis longipes. Both alkaloids showed high efficacy individually (in concentration of 50-150 ppm) and also in a 1:1 mixture against spore germination of some fungi, viz. Alternaria alternata, A. brassicae, Curvularia maculans, Curvularia sp., Colletotrichum gloeosporioides, Colletotrichum sp., Helminthosporium speciferum, H. pennisetti, Helminthosporium sp., and Ustilago cynodontis.
CONCLUSIONS:
The antifungal effect of single compounds was dose-dependent.
If the mutual ratio of the two components in the mixture was changed from 1:1 to a major content of any of the two compounds, the inhibitory effect on spore germination decreased.
Nat Prod Res. 2009;23(3):250-5.
New alkaloids from Corydalis species.[Pubmed:
19235025]
METHODS AND RESULTS:
A new alkaloid, chaerophylline (1), together with known alkaloids (-)-corypalmine, berberine chloride, (-)-isocorypalmine, (-)-corydalmine and (+)-bicuculline have been isolated from the crude base fraction of Corydalis chaerophylla. The crude base fractions of Corydalis longipes gave a new alkaloid, longicine (4), together with known alkaloids (+/-)-alpha-hydrastine, (+/-)-beta-hydrastine, N-methylhydrasteine hydroxylactam, 1-Methoxyberberine chloride and berberinium hydroxide.
CONCLUSIONS:
These alkaloids are reported for the first time from the above species and their structures were established by chemical and spectroscopic evidence.
