Oxymatrine
Catalog No: CFN99805
Oxymatrine has exhibited anti-hepatitis virus infection, anti-hepatic fibrosis, anti-inflammation, anti-anaphylaxis and other immune-regulation, it induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome C. It can attenuate diabetes-associated cognitive deficits in rats, which is associated with oxidative stress, inflammation and apoptotic cascades, it is proven to protect ischemic and reperfusion injury in liver, intestine and heart.
Deoxypodophyllotoxin
Catalog No: CFN99888
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities. Deoxypodophyllotoxin induces G2 /M cell-cycle arrest followed by apoptosis through multiple cellular processes, involving the activation of ATM, upregulation of p53 and Bax, activation of caspase-3 and -7, and accumulation of PTEN resulting in the inhibition of the Akt pathway. Deoxypodophyllotoxin maybe applicable to treat hyperpigmentation, it decreases UV-induced skin pigmentation of brown guinea pigs.
Atractylenolide III
Catalog No: CFN99946
Atractylenolide III, a potential house dust mite control agent, has neuroprotection, gastroprotective, anti-cancer, and anti-inflammatory activities, it also may control immunological reactions by regulating the cellular functions of IL-6 in mast cells. It inhibited nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophages, and inhibited Lipopolysaccharide-induced TNF- α and NO production in macrophages.
