Genotoxicity

2,6-Dimethoxy-1,4-benzoquinone
Catalog No: CFN98883

2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ug/mL, and MBC values of 7.8, 7.8, and 31.2  ug/mL, respectively. 2,6-Dimethoxy-1,4-benzoquinone can produce genotoxic effects in patients taking dimethophrine.

Ligularizine
Catalog No: CFN00379

Ligularizine, ligularidine, and neoligularidine are possibly genotoxic carcinogens.

Isatidine
Catalog No: CFN00408

Isatidine and sceleratine slightly raise blood pressure in cats following intravenous injection, and stimulate isolated guinea pigs' uteri. Isatidine shows in vitro genotoxicity in Hep G2/SCGE assays.

Integerrimine
Catalog No: CFN00419

Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.

Riddelline
Catalog No: CFN00421

Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.