Cytotoxic

30-Hydroxygambogic acid
Catalog No: CFN92101

30-Hydroxygambogic acid exhibits significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines.

9,10-Dimethoxycanthin-6-one
Catalog No: CFN92127

9,10-Dimethoxycanthin-6-one shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 5.0 microM).

Eurycomalactone
Catalog No: CFN92129

Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. It shows antiplasmodial activity against Gombak A isolate. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)].

Chamaejasmine
Catalog No: CFN92154

Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and induces Bax expression to desintegrate the outer mitochondrial membrane and causes cytochrome c release.

Salviolone
Catalog No: CFN92163

Salviolone exhibits cytotoxic activity against Vero cells.