Anxiolytic

Orcinol
Catalog No: CFN98796

Orcinol glucoside is anxiolytic agent without sedative effect, it improves depressive behaviour in CUMS rats by downregulating HPA axis hyperactivity and increasing BDNF expression and ERK1/2 phosphorylation in the hippocampus.

beta-Amyrin
Catalog No: CFN98935

beta-Amyrin has antiviral, hepatoprotective, antinociceptive, anti-inflammatory, it retard acute inflammation in rat model of periodontitis. Beta-Amyrin can enhance the total sleeping behavior in pentobarbital-induced sleeping model via the activation of GABAergic neurotransmitter system through GABA content in the brain.alpha- and beta-Amyrin mixture has gastro-protective activity, the mechanism involves at least in part the activation of capsaicin-sensitive primary afferent neurons; it also has sedative and anxiolytic effects, the mechanism may involve an action on benzodiazepine-type receptors, and also an antidepressant effect where noradrenergic mechanisms will probably play a role.

Valepotriate
Catalog No: CFN90205

Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agents for the HTC hepatoma cells. Valepotriates may have a potential anxiolytic effect on the psychic symptoms of anxiety. Valepotriate fraction can have sedative effects and affect behavioral parameters related to recognition memory.

(-)-Hinokinin
Catalog No: CFN92255

(-)-Hinokinin has anti-genotoxic and anticarcinogenic potential. (-)-Hinokinin is an anti-chagasic drug, has no mutagenic effects in animal cell and bacterial systems, anxiety that target the DAT, NET, and GAT-1 transporters, it may serve as a tool to develop new therapeutic drugs for attention deficit hyperactivity disorder.

Trimethylgallic acid
Catalog No: CFN92508

Trimethylgallic acid esters are potent antioxidants and inhibitor of cytokine production, can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice, showing protective effects against chronic stress; they also exert hepatoprotective effects in CCl4-induced rats, specifically by modulating oxidative-nitrosative stress and inflammation.