Anxiolytic

Isopulegol
Catalog No: CFN98126

Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GABAA receptors and to antioxidant properties.Isopulegol presents significant gastroprotective effects in both ethanol- and indomethacin-induced ulcer models, which appear to be mediated, at least in part, by endogenous prostaglandins, K(ATP) channel opening, and antioxidant properties.

Phaseollidin
Catalog No: CFN98611

Phaseollidin, a phytoalexin from Phaseolus vulgaris, has antimicrobial activity. It also has anti-anxiety properties.

Gelsevirine
Catalog No: CFN98622

Gelsevirine has anxiolytic activity, may be via the agonist action of glycine receptor in the brain. Gelsevirine can significantly inhibit the proliferation of human carcinoma cell line SW480 and MGC80-3 in a dose-dependent manner, the 50% inhibiting concentration(IC50)of gelsevirine on SW480 cells and MGC80-3 cells are 1.41±0.06 mM and 1.22±0.11 mM respectively.

4-Aminobutanoic acid
Catalog No: CFN90028

Lower CSF 4-Aminobutanoic acid may explain increasing severity of psychic anxiety in major depression with increasing age, suggests treatments targeting the 4-Aminobutanoic acid ergic system should be evaluated in treatment-resistant anxious major depression and in older patients.

Chrysin
Catalog No: CFN98741

Chrysin, a naturally-occurring ligand for benzodiazepine receptors, with anticonvulsant , anti-inflammation, anti-cancer, hepatoprotective, and anti-oxidation properties. Chrysin induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells; it prevented the development of DN in HFD/STZ-induced type 2 diabetic rats through anti-inflammatory effects in the kidney by specifically targeting the TNF-α pathway.