Anticancer

Bisdemethoxycurcumin
Catalog No: CFN99186

Bisdemethoxycurcumin is a natural derivative of curcumin with antiulcer, antioxidant, anti-inflammatory and anti-cancer activities, it suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. Bisdemethoxycurcumin induces apoptosis in activated HSCs, but not in hepatocytes, by impairing cellular energetics and causing a downregulation of cytoprotective proteins, likely through a mechanism that involves CBR2.

Curcumol
Catalog No: CFN99187

Curcumol has antitumor, anti-inflammatory, and anti-seizure actions. It suppressed RANKL-induced osteoclast formation by attenuating the JNK signaling pathway, and inhibited Jak2-STAT signal pathway molecules of fibroblast-like synoviocytes in patients with rheumatoid arthritis. It is a novel anti-seizure agent which inhibited neuronal excitability through enhancing GABAergic inhibition.

Hypericin
Catalog No: CFN99188

Hypericin is a photosensitive antiviral with anticancer and antidepressant agent . It can inhibit tyrosine kinases with IC50 of 7.5 μM. It can induce both apoptosis and necrosis in a concentration and light dose-dependent fashion, and inhibit RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.

Caffeic acid
Catalog No: CFN99190

Caffeic acid has antidiabetic, antioxidant, anticarcinogenic, and anti-inflammatory activities, it can suppress ultraviolet B(UVB)-induced COX-2 expression by blocking Fyn kinase activity, inhibits HBV-DNA replication as well as HBsAg production, also reduces serum DHBV level in DHBV-infected duckling model. Caffeic acid may be used as designed novel therapeutic drugs for Parkinson's disease by inhibiting α-synuclein fibrillation.

D-Glucosamine hydrochloride
Catalog No: CFN99194

D-glucosamine hydrochloride has antimicrobial effect on the common 21 strains of food spoilage microorganisms, it could as preservative agent was used to preserve nature eleo juice. D-glucosamine hydrochloride also has antitumor, antiinflammaty, and anti-arthritis effects, it induces cell apoptosis by blocking of cell-cycle.