Antibacterial

Murrangatin
Catalog No: CFN98604

Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein–Barr virus early antigen (EBV–EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. Murrangatin exhibits antibacterial activity against P. gingivalis (ATCC 33277). Murrangatin also shows soluble epoxide hydrolase inhibitory activity with IC50 values 13.9±6.5uM. Murrangatin and murracarpin may be a new backbone for developing inhibitors of cyclooxygenase 2, they show chondroprotective activity by downregulation of interleukin-1β, tumor necrosis factorα, prostaglandins E2,and matrix metalloproteinases -13, and both of them may be a new backbone for developing inhibitors of cyclooxygenase 2.

7,4'-Dihydroxy-3'-prenylflavan
Catalog No: CFN98606

7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity.

Anethole
Catalog No: CFN98550

Anethole has antispasmodic, anti-inflammatory, cardiovascular, and gastroprotective effects. Anethole can act as the CXCR4 antagonist and as the PTEN activator which resulted to PI3K/AKT-mediated inhibition of the metastatic prostate cancer progressions. Anethole may have a potent inhibitory effect on PD through suppression of pro-inflammatory molecules, it could be a novel therapeutic strategy for Periodontitis. Anethole blocks neuronal excitability,and induces the blockade of neuromuscular transmission. trans-Anethole has insecticidal activity to adult fruit flies of Ceratitis capitata, Bactrocera dorsalis, and Bactrocera cucurbitae.

Atractyloside A
Catalog No: CFN98560

Atractyloside is a toxic compound from wedelia glauca. It acts as inhibitor of oxidative phosphorylation by a specific interference with energy-transfer reactions, the effect is due to inhibition of the ADP utilizing process in the coupling system. Atractyloside, has been proposed for the antibiotic oligomycin, is an inhibitor of the energy-transfer reactions in animal mitochondria; it inhibits the phosphate uptake and the respiratory stimulation induced by P1-acceptor, but it does not interfere with the so-called resting respiration.

Cordycepin
Catalog No: CFN98566

Cordycepin possesses immunological stimulating,anti-hyperglycemia, anti-cancer, neuroprotective, antifungal, antibacterial, anti-inflammatory, anti-virus and anti-infection activities. Cordycepin has inhibitory effects on osteoclast differentiation in vitro and that it suppresses inflammatory bone loss in vivo. Cordycepin inhibited the production of NO production by down-regulation of iNOS and COX-2 gene expression via the suppression of NF-κB activation, Akt and p38 phosphorylation, suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b.