Nuciferine
Catalog No: CFN99733
Nuciferine possesses anti-diabetic, anti-obesity, anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, vasorelaxant, and insulin secretagogue activities. Nuciferine may be potential for the prevention and treatment of hyperuricemia with kidney inflammation. It inhibited tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer.
Dauricine
Catalog No: CFN98129
Dauricine may has neuroprotective, and anti-tumor effects, it can pass the blood‑brain barrier, and that P‑glycoprotein has an important role in the transportation of Dauricine across the blood‑brain barrier, it can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes. Dauricine also has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A.
Crebanine
Catalog No: CFN98275
Crebanine has antiarrhythmic, anticancer, anti-inflammatory,
and analgesic properties; it can significantly improve the cognitive deficits induced by scopolamine, via the alpha-7 nicotinic acetylcholine receptor, crebanine or its scaffold can be used as the starting point to develop a drug for Alzheimer's disease.Crebanine can reduce TNF-α-induced cancer cell proliferation, invasion, and survival by suppressing NF-κB activity and expression profile of its downstream genes.