Nonivamide
Catalog No: CFN90179
Nonivamide, present in chili peppers, is commonly manufactured synthetically and used as a food additive to add pungency to seasonings, flavorings, and spice blends.
Nonivamide and capsaicin are novel skin permeation enhancers for indometacin.
Nonivamide has antioxidant, anti-obesity, and anti-inflammatory effects, it reduces energy intake, enhances energy metabolism, decreases serum triacylglycerol content, and inhibits adipogenesis via activation of the transient receptor potential cation channel subfamily V member 1 (TRPV1).
Prunetin
Catalog No: CFN90189
Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones.