Ethyl 4-methoxycinnamate
Catalog No: CFN98180
Ethyl p-methoxycinnamate(Ethyl 4-methoxycinnamate) has antifungal activity, it can inhibit the growth of Trichophyton rubrum, Aspergillus niger, Saccharomyces cerevisiae and Epidermophyton floccosum at a concentration less than 10 mug/ml. Ethyl-p-methoxycinnamate has anti-inflammatory, it can dose-dependently inhibit carrageenan-induced edema with an MIC of 100 mg/kg, and non-selectively inhibit the activities of cyclooxygenases 1 and 2, with IC50 values of 1.12 uM and 0.83 uM respectively; it has chemopreventive activity against fibrosarcoma through inhibition of COX-2, and can block bFGF-induced vessel formation on Matrigel plug assay in vivo. Ethyl p-methoxycinnamate could be developed as a skin whitening agent to treat hyperpigmentary disorders.
Taxifolin
Catalog No: CFN98734
Taxifolin exhibits important anti-tyrosinase activity, it also exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM.Taxifolin has anti-oxidant, anti-melanogenic, chemopreventive, anti-inflammatory, and cardioprotective effects. Taxifolin promotes osteoblast differentiation in MC3T3-E1 cells and also inhibit osteoclastogenesis in RAW264.7 cells, it also can enhance andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation.