Pyranojacareubin

Pyranojacareubin
Product Name Pyranojacareubin
CAS No.: 78343-62-1
Catalog No.: CFN89137
Molecular Formula: C23H20O6
Molecular Weight: 392.40 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The stem barks of Calophyllum inophyllum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Pyranojacareubin is a natural product from Calophyllum inophyllum.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • bioRxiv-Pharm.&Toxi.2022, 2022.481203.
  • Journal of Molecular Liquids2021, 334:116014.
  • Sci Rep.2023, 13(1):7475.
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • Foods.2023, 12(7):1355.
  • Int J Mol Sci.2019, 20(11):E2734
  • J Mol Histol.2019, 50(4):343-354
  • Neurochem Res.2021, s11064-021-03449-0
  • Jeju National University Graduate School2023, 24478
  • Hum Exp Toxicol.2022, 41:9603271221143713.
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    Pak J Pharm Sci. 2015 Mar;28(2):425-9.
    Antiproliferative xanthone derivatives from Calophyllum inophyllum and Calophyllum soulattri.[Pubmed: 25730799]

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    Structure-activity relationships of eleven xanthones were comparatively predicted for four cancer cell lines after the compounds were subjected to antiproliferative assay against B-lymphocyte cells (Raji), colon carcinoma cells (LS174T), human neuroblastoma cells (IMR-32) and skin carcinoma cells (SK-MEL-28). The eleven chemical constituents were obtained naturally from the stem bark of Calophyllum inophyllum and Calophyllum soulattri. Inophinnin (1) and inophinone (2) were isolated from Calophyllum inophyllum while soulattrin (3) and phylattrin (4) were found from Calophyllum soulattri. The other xanthones were from both Calophyllum sp. and they are Pyranojacareubin (5), rheediaxanthone A (6), macluraxanthone (7), 4-hydroxyxanthone (8), caloxanthone C (9), brasixanthone B (10) and trapezifolixanthone (11).
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    METHODS AND RESULTS:
    The stem bark extracts of Calophyllum inophyllum furnished one new furanoxanthone, inophinnin (1), in addition to inophyllin A (2), macluraxanthone (3), Pyranojacareubin (4), 4-hydroxyxanthone, friedelin, stigmasterol, and betulinic acid. The structures of these compounds were determined by spectroscopic analysis of 1D and 2D NMR spectral data ((1)H, (13)C, DEPT, COSY, HMQC, and HMBC) while EI-MS gave the molecular mass.
    CONCLUSIONS:
    The new xanthone, inophinnin (1), exhibited some anti-inflammatory activity in nitric oxide assay.
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