Hedragonic acid
Hedragonic acid is a natural product from Dryobalanops aromatica.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Molecules.2019, 24(23):E4303
J Med Food.2021, 24(3):209-217.
Plant Direct.2021, 5(12):e372.
Separations2021, 8(6),80.
Front Pharmacol.2020, 11:566490.
J Appl Microbiol.2024, 135(7):lxae180.
Mol Med Rep.2024, 29(2):26.
Kor. J. Herbol.2022, 37(5): 89-96.
Nat Commun.2023, 14(1):8142.
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Phytochemistry, 1972, 11(5):1771-80.
Structures of triterpenes from Dryobalanops aromatica.[Reference:
WebLink]
METHODS AND RESULTS:
Further constituents of Dryobalanops aromatica resin include oleanolic acid acetate, Hedragonic acid, and dryobalanonoloic acid, shown to be 20(S)-20-hydroxydammar-24-en-3-on-21-oic acid. Also isolated (in the form of 3,23-O-isopropylidene derivatives) were methyl 11-oxoasiatate and dryobalanolide, shown to be 2α,3β,23-trihydroxyursa-11-en-13β,28-olide.
CONCLUSIONS:
The structural and possible biogenetic relationship between the 17 triterpenes so far isolated from the resin is discussed.
