27-p-Coumaroyloxyursolic acid

27-p-Coumaroyloxyursolic acid
Product Name 27-p-Coumaroyloxyursolic acid
CAS No.: 73584-67-5
Catalog No.: CFN97217
Molecular Formula: C39H54O6
Molecular Weight: 618.9 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Viburnum cylindricum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Cell Signal.2022, 99:110433.
  • Int J Mol Sci.2022, 23(10):5813.
  • Front Pharmacol.2023, 14:1095083.
  • Anal Bioanal Chem.2018, 410(5):1561-1569
  • University of Stuttgart2021, 11682.
  • Materials Today Communications2023, 37:107216
  • Evid Based Complement Alternat Med.2016, 2016:1230294
  • J Med Food.2020, 23(6):633-640.
  • Food Science and Human Wellness2022, 11(4):965-974
  • Int J Mol Sci.2023, 24(18):14077.
  • 27-p-Coumaroyloxyursolic acid

    Catalog No: CFN97217
    CAS No: 73584-67-5
    Price: Inquiry(manager@chemfaces.com)
    Quinovic acid

    Catalog No: CFN98694
    CAS No: 465-74-7
    Price: Inquiry(manager@chemfaces.com)
    Quinovic acid 3-O-alpha-L-rhamnopyranoside

    Catalog No: CFN99060
    CAS No: 104055-76-7
    Price: Inquiry(manager@chemfaces.com)
    Quinovin

    Catalog No: CFN99084
    CAS No: 107870-05-3
    Price: Inquiry(manager@chemfaces.com)
    Quinovic acid 3-O-(3',4'-O-isopropylidene)-beta-D-fucopyranoside

    Catalog No: CFN99850
    CAS No: 182132-59-8
    Price: Inquiry(manager@chemfaces.com)
    Quinovic acid 3-O-beta-D-glucoside

    Catalog No: CFN97273
    CAS No: 79955-41-2
    Price: Inquiry(manager@chemfaces.com)
    Rubelloside B

    Catalog No: CFN99801
    CAS No: 167875-39-0
    Price: Inquiry(manager@chemfaces.com)
    Quinovic acid 3-O-(6-deoxy-beta-D-glucopyranoside) 28-O-beta-D-glucopyranosyl ester

    Catalog No: CFN99361
    CAS No: 124727-10-2
    Price: Inquiry(manager@chemfaces.com)
    J Nat Prod. 1999 Jul;62(7):1061-4.
    Activity-guided isolation of triterpenoid acyl CoA cholesteryl acyl transferase (ACAT) inhibitors from Ilex kudincha.[Pubmed: 10425145 ]

    METHODS AND RESULTS:
    Activity-guided fractionation of a methanol extract of the leaves of Ilex kudincha led to the isolation of seven acyl CoA cholesteryl acyl transferase (ACAT) inhibitory triterpenes. Four of them were identified by spectroscopic methods as ulmoidol (4), 23-hydroxyursolic acid (5), 27-trans-p-coumaroyloxyursolic acid (6), and 27-cis-p-coumaroyloxyursolic acid (7), and three were new compounds named ilekudinols A-C (1-3). The structures of these new triterpenoids were elucidated as 2alpha, 3beta-dihydroxy-24-nor-urs-4(23),11-dien-28,13beta- olide (1), 2alpha, 3beta-dihydroxy-24-nor-urs-4(23),12-dien-28-oic acid (2), and 3beta, 24,28-trihydroxylupane (3).
    CONCLUSIONS:
    Compounds 1-7 showed potent inhibitory activity in the ACAT assay.
    Planta Med. 2001 Oct;67(7):683-4.
    Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid.[Pubmed: 11582553 ]

    METHODS AND RESULTS:
    The triterpenes ursolic acid (1), 27-p-Z-coumaroyloxyursolic acid (2), 27-p-E-coumaroyloxyursolic acid, alpha-amyrine-3-palmitate and lupeol-3-palmitate were isolated through a bioactivity-guided fractionation from the acetonic extract of the aerial parts of Viburnum jucundum Morton in addition to amentoflavone, an epimeric mixture at C-2 of 2,3-dihydroamentoflavone, beta-sitosterol and beta-sitosteryl glucopyranoside.
    CONCLUSIONS:
    Ursolic acid (1) was the only constituent that exhibited cytotoxic activity toward three human cancer cell lines in culture. This is the first phytochemical and cytotoxic analysis performed to this plant species.
    Selaginellin F

    Catalog No: CFN95029
    CAS No: 1340493-24-4
    Price: $413/5mg
    Arjungenin

    Catalog No: CFN95039
    CAS No: 58880-25-4
    Price: $318/20mg
    Betmidin

    Catalog No: CFN95047
    CAS No: 35589-22-1
    Price: $413/5mg
    Magnaldehyde B

    Catalog No: CFN95075
    CAS No: 92829-72-6
    Price: $318/5mg
    Bruceoside A

    Catalog No: CFN95080
    CAS No: 63306-30-9
    Price: $368/20mg
    Asiaticoside B

    Catalog No: CFN95124
    CAS No: 125265-68-1
    Price: $158/20mg
    1,7-Diphenyl-5-hydroxy-4,6-hepten-3-one

    Catalog No: CFN95171
    CAS No: 87095-77-0
    Price: $318/10mg
    Euphorbia factor L25

    Catalog No: CFN95339
    CAS No: 303174-98-3
    Price: $368/5mg
    Yinxiancaoside C

    Catalog No: CFN95377
    CAS No: 1159908-74-3
    Price: $413/5mg
    Ganoderenic acid K

    Catalog No: CFN95469
    CAS No: 942950-94-9
    Price: $318/10mg