Neuroprotection

Paeonilactone C
Catalog No: CFN96056

Paeonilactone C significantly protects primary cultures of rat cortical cells against H2O2-induced neurotoxicity.

Syzalterin
Catalog No: CFN96061

Syzalterin can protect PC12 cells effectively against Abeta-induced toxicity.

Harman
Catalog No: CFN96092

Harman exhibits neuroactive activity in the human body.

Moracin O
Catalog No: CFN96102

Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 uM. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.

3,6'-Disinapoyl sucrose
Catalog No: CFN90578

3,6'-Disinapoyl sucrose has neuroprotective effect and antidepressive activity in rats, at least in part, by increasing expression of cyclic AMP response element (CRE)-binding protein (CREB) and its downstream target protein, brain-derived neurotrophic factor (BDNF). 3,6'-Disinapoyl sucrose protect neuron cells from glutamate-induced excitotoxicity include the downregulation of proapoptotic gene Bax and the upregulation of antiapoptotic gene Bcl-2.