Inhibitors

Imbricatolic acid
Catalog No: CFN97164

Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells.

6',7'-Dihydroxybergamottin acetonide
Catalog No: CFN97165

6',7'-Dihydroxybergamottin is a potent inhibitor of CYP3A activity, and may be primarily responsible for the effects of grapefruit juice on cytochrome P450 activity in humans.

Heliotrine
Catalog No: CFN00270

The pyrrolizidine alkaloid Heliotrine interferes with reporter signals derived from GAL4-based nuclear receptor transactivation assays by a mechanism independent of luciferase enzyme inhibition. Acute hepatitis induced by Heliotrine is accompanied by uncoupling of oxidative phosphorylation in liver mitochondria.

Sempervirine
Catalog No: CFN97173

Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA .

Macrophylline
Catalog No: CFN00275

Macrophylline A shows weak inhibitory action on KCl-induced contraction.