Inhibitors

Antibiotic ZG 1494alpha
Catalog No: CFN00130

Antibiotic ZG 1494alpha is a novel inhibitor of platelet-activating factor (PAF) acetyltransferase. It also exhibits antifungal activity against Candida albicans.
Decarine
Catalog No: CFN98909

Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.
Calystegine C2
Catalog No: CFN00160

Calystegine C2, the 2-epimer of calystegine C1, exhibits an inhibitory activity against beta-glucosidase and beta-galactosidase.
Mollugin
Catalog No: CFN98930

Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Mollugin has anticancer efficacy, can modulate the HER2, HO-1, Nrf2 , and NF- κB pathways.
Friedelin
Catalog No: CFN98936

Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities.Friedelin rich fraction (IND-HE) shows estrogenic activity as indicated by vaginal cornification, increase in uterine weight and rise in serum estrogen. Friedelin may be beneficial to mimic insulin action that would be useful in the treatment of diabetes type 2 patients.