Antithyroid

Glucosylvitexin
Catalog No: CFN99139

Glucosylvitexin can inhibit thyroid peroxidase (TPO) activity, thus it can produce goitrogenic and antithyroid effects similar to those of certain other antithyroid agents and small doses of methimazole (MMI).

Periplogenin
Catalog No: CFN90514

Periplogenin plays protective roles against thyrotoxicosis and associated cardiovascular problems, are mediated through its direct antithyroidal and/or LPO inhibiting properties. Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models.

Goitrin
Catalog No: CFN90623

Goitrin is a potent antithyroid compound, it is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase,leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine. Goitrin is responsible for the induction of glutathione S-transferases.