Anti-inflammatory

Corylifol A
Catalog No: CFN92226

Corylifol A is a naturally occurring potent inhibitor of hCE2 and UDP-glucuronosyltransferase 1A1 (UGT1A1); it could be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A has antiinflammatory activity, it shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uΜ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells.

Delta 7-avenasterol
Catalog No: CFN92240

Delta 7-avenasterol has antioxidant activity.

Ponicidin
Catalog No: CFN92259

Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infection. Ponicidin has anti-cancer activity against gastric carcinoma and lung cancer; can inhibit growth and induce apoptosis of gastric carcinoma cell line MKN28, via the signaling pathway regulated by Janus kinase 2 (JAK2) and signal transducers and activators of transcription 3 (STAT3).

Platyconic acid A
Catalog No: CFN92268

Platyconic acid A suppresses the development of respiratory inflammation, hyperresponsiveness, and remodeling by reducing allergic responses, and it may be a potential herbal drug for allergen-induced respiratory disease prevention. Platyconic acid A suppresses PMA-induced MUC5AC mRNA expression by inhibiting NF-κB activation via Akt in A549 cells.

Deapi-platycodin D3
Catalog No: CFN92269

Deapi-platycodin and platycodinD, aqueous extract of the root of Platycodon grandiflorum A. de Candolle (APG), can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonary diseases.