Antipsychotic

Saikosaponin B1
Catalog No: CFN99127

Saikosaponin B1 may be as anti-schizophrenic candidate drugs, it can suppress the signal transduction after binding of EGF.

Pregnenolone
Catalog No: CFN99497

Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively. Pregnenolone has memory-enhancing effects, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.

Quetiapine fumarate
Catalog No: CFN98513

Quetiapine fumarate monotherapy (150 mg/day and 300 mg/day) is effective, with safety and tolerability in the treatment of patients with major depressive disorder. Quetiapine fumarate can treat patients with schizophrenia.

Gentianine
Catalog No: CFN98674

Gentianine has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, and diuretic actions, it could be developed as a safe antihypertensive drug. Gentianine has a protective effect on hippocampal CA1 neurons in rats subjected to recurrent febrile convulsion (FC), it can ameliorate FC-induced neuronal injury by enhancing glutamate acid decarboxylase activity, decreasing glutamate levels and increasing γ-aminobutyric acid levels.

Ramelteon
Catalog No: CFN90021

Ramelteon is a novel MT1 and MT2 melatonin receptor selective agonist recently approved for insomnia treatment, it could be a potential therapeutic drug, in adjunctive treatment of learning and memory deficits seen in patients with schizophrenia, it is effective for the prevention of delirium, ramelteon administered nightly to elderly patients admitted for acute care may provide protection against delirium. Ramelteon significantly improves symptoms in patients with gastroesophageal reflux disease and significantly improves patients' sleep experience.