Anti-trypanosoma

Argentinine
Catalog No: CFN96081

Argentinine exhibits significant activity against Trypanosoma cruzi.

Primin
Catalog No: CFN90588

Primin has antimycobacterial, and strong antineoplastic actions. Primin has potent activity against Trypanosoma brucei rhodesiense (IC50 0.144 microM) and Leishmania donovani (IC50 0.711 microM), and low cytotoxicity (IC50 15.4 microM) on mammalian cells; it could serve as a lead compound for the rational design of more potent and less toxic antiprotozoal agents.

Taccalonolide A
Catalog No: CFN90596

Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects.

Taccalonolide B
Catalog No: CFN90602

Taccalonolide B displays microtubule stabilizing activity.Several taccalonolides have in vitro antitrypanosomal activity against Trypanosoma brucei brucei and EC50 values for the isolated compounds were from 0.79 ug/mL.

Ajugol
Catalog No: CFN90759

Ajugol shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).